Flea and tick are the most common problem that pets face. These nasty parasites cause discomfort, skin irritation and even lead to wide range of diseases like flea allergy dermatitis (FAD), anemia or other internal parasites including tapeworm, and rickettsiosis.
With those conditions, your pet feels lethargic, and faces lot of problems. It adversely affects his health in numerous ways.
Most pet owners search for the best ways to remove these flea and ticks. Among the wide range of flea and tick treatments available in the market, Frontline Plus is the most popular and highly effective. Moreover, many veterinarians also recommend this topical solution for treating the harmful flea infestations.
However, while purchasing this flea and tick spot-on treatment online, many pet owners are confused between Frontline Plus and Frontline Combo. They are placed in the dilemma whether to buy ‘Plus’ pack or ‘Combo’ pack, what is the difference between them, and which is the most effective one that fights against fleas and ticks.
Well, to clear all your confusion, we present here the solution for this “frequently asked question”, with a short description about each product and help you understand the difference between them.
Frontline Plus is a flea and tick treatment available in the U.S. This over-the-counter medication is the most popular topical solution for treating fleas and ticks. It removes fleas along with ticks and lice on pets. Further, it stops flea infestation by killing adult fleas and acts as flea repellant. More importantly, it does not just kill adult fleas and ticks but destroys the next generation of flea eggs and larvae.
Frontline Plus is highly recommended by veterinarians due to its powerful effect in protecting dogs from infestation for longer period. It continuously has its effect for a month on dogs and cats.
Frontline Plus is known as Frontline Combo in U.K. and Europe.
Frontline Combo is a prescription medication in the U.K. It is widely used to treat and control fleas and ticks. As many fleas are resistant to original Frontline available in the U.K market, Frontline Combo works effectively. It stops the fleas laying eggs, and breaks the lifecycle of fleas. Furthermore, it disrupts the other flea life stages around the house through pet hair, which has been induced with life stage inhibitors, when you treat the pet to kill the adult fleas.
Manufactured by the brand company Merial to kill fleas at all stages, Frontline Combo further prevents recurrence of fleas and ticks on your pets. It effectively controls flea and tick on dogs and cats, puppies and kittens helping them to stay healthy year round. Additionally, Frontline Combo is widely popular due to its scientific proven methodology that kills flea eggs and flea larvae further preventing re-infestation in dogs and cats.
Not only for fleas, but Frontline Combo is also designed to fight against all stages of ticks including brown dog tick, the American dog tick, lone star tick and deer ticks, (which is the major carrier of Lyme disease).
Frontline Combo shows the same benefits as the Frontline Plus whereas the difference lies in their names depending on the countries where they are sold.
Some of the most important features of Combo/Frontline Plus are:
Frontline Plus, the American version and Frontline Combo, sold in Europe, contains fipronil and the insect growth regulator (IGR) (S)-methoprene. These active ingredients effectively target all stages of fleas. Filbronil stays in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in long-lasting activity against fleas, ticks and chewing lice.
Find Below the basic difference between Frontline Plus and Frontline Combo
Frontline for Dogs:
USA Version –
UK Version –
Overall, Frontline U.S. version is Frontline Plus and U.K. version is Frontline Combo. Except for some of the material differences, there is no major difference between these two products. According to the climate and types of fleas and ticks in the respective countries, both the products work perfectly in treating and protecting your dogs and cats from the external parasites.