Flea and tick are the most common problem that pets face. These nasty parasites cause discomfort, skin irritation and even lead to wide range of diseases like flea allergy dermatitis (FAD), anemia or other internal parasites including tapeworm, and rickettsiosis. 

With those conditions, your pet feels lethargic, and faces lot of problems. It adversely affects his health in numerous ways.

Most pet owners search for the best ways to remove these flea and ticks. Among the wide range of flea and tick treatments available in the market, Frontline Plus is the most popular and highly effective. Moreover, many veterinarians also recommend this topical solution for treating the harmful flea infestations.
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However, while purchasing this flea and tick spot-on treatment online, many pet owners are confused between Frontline Plus and Frontline Combo. They are placed in the dilemma whether to buy ‘Plus’ pack or ‘Combo’ pack, what is the difference between them, and which is the most effective one that fights against fleas and ticks.

Well, to clear all your confusion, we present here the solution for this “frequently asked question”, with a short description about each product and help you understand the difference between them.

Frontline Combo

Frontline Plus is known as Frontline Combo in U.K. and Europe.
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Frontline Combo is a prescription medication in the U.K. It is widely used to treat and control fleas and ticks. As many fleas are resistant to original Frontline available in the U.K market, Frontline Combo works effectively. It stops the fleas laying eggs, and breaks the lifecycle of fleas. Furthermore, it disrupts the other flea life stages around the house through pet hair, which has been induced with life stage inhibitors, when you treat the pet to kill the adult fleas.

 Manufactured by the brand company Merial to kill fleas at all stages, Frontline Combo further prevents recurrence of fleas and ticks on your pets. It effectively controls flea and tick on dogs and cats, puppies and kittens helping them to stay healthy year round. Additionally, Frontline Combo is widely popular due to its scientific proven methodology that kills flea eggs and flea larvae further preventing re-infestation in dogs and cats. 

Not only for fleas, but Frontline Combo is also designed to fight against all stages of ticks including brown dog tick, the American dog tick, lone star tick and deer ticks, (which is the major carrier of Lyme disease).
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​Frontline Combo shows the same benefits as the Frontline Plus whereas the difference lies in their names depending on the countries where they are sold. 

Frontline Plus 

Frontline Plus is a flea and tick treatment available in the U.S. This over-the-counter medication is the most popular topical solution for treating fleas and ticks. It removes fleas along with ticks and lice on pets. Further, it stops flea infestation by killing adult fleas and acts as flea repellant. More importantly, it does not just kill adult fleas and ticks but destroys the next generation of flea eggs and larvae.

Frontline Plus is highly recommended by veterinarians due to its powerful effect in protecting dogs from infestation for longer period. It continuously has its effect for a month on dogs and cats. 

Some of the most important features of Combo/Frontline Plus are:

• It stops and prevents flea and tick infestations.
• It prevents all flea stages starting from eggs, larvae to pupae developing.
• Frontline Combo effectively kills adult fleas, flea eggs, and flea larvae.
• It kills fleas that may cause flea allergy dermatitis.
• It completely helps control re-infestations.
• This flea and tick treatment rapidly eliminates infestations caused due to chewing lice. 
• This topical solution has long lasting effect and thus, keeps away fleas and ticks for a longer period.
• With its fast-acting property, it removes all fleas and ticks within few hours.
•  Being waterproof, there is no worry whether your dog goes for swimming or        bathing. 
• Due to its ergonomic design, Frontline Plus is convenient to use. 
• It does not have any side effects so can be used on breeding, pregnant and lactating queens. 
•   It is also beneficial in controlling sarcoptic mange infestations. 
• It kills all stages of ticks including brown dog ticks, deer ticks, American dog ticks and lone star ticks. 

Frontline Plus, the American version and Frontline Combo, sold in Europe, contains fipronil and the insect growth regulator (IGR) (S)-methoprene. These active ingredients effectively target all stages of fleas. Filbronil stays in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in long-lasting activity against fleas, ticks and chewing lice.

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Find Below the basic difference between Frontline Plus and Frontline Combo

Frontline for Dogs:

USA Version –

• Dosage - 0.045 fl oz (1.34 ml)
• Active Ingredients - 9.8% Fipronil & 8.8% (S)-Methoprene (by weight)
• For dogs - 23-44 lbs

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UK Version –

• Dosage - 1.34 mL
• Active Ingredients - 100 g/L Fipronil & 90 g/L (S)-Methoprene (by volume)
• For dogs - 10-20 kgs

In this economy, all of us are looking for ways to save money in every possible way. Pet owners, with concern for their furry friends, search for the best ways to keep their expenses down, without comprising on their pet’s care. Although, it is not possible to cut down vet visits during emergencies or preventive treatments, there are simple ways to cut back on big expenses without sacrificing on real care.